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24votes

Best expression system for a stable antigen in tomato?

Comparing transient (agroinfiltration) vs. stable transformation for yield and immunogenicity. What's the consensus for edible delivery?

Dr. R. HaqueDr. R. HaqueExpressionTomato
11 replies1.2k views2h ago
31votes

Mucosal IgA response — a reading list for students?

Compiling an approachable intro to gut mucosal immunity for new forum members. Suggestions for foundational papers welcome.

M. KarimM. KarimImmunityEducation
15 replies2.4k views5h ago
18votes

Cold-chain-free delivery: what's realistic by 2030?

Looking for evidence on dosing consistency and antigen stability in edible formats across variable storage conditions.

S. AkterS. AkterAccessPolicy
7 replies890 views1d ago
15votes

Regulatory pathway for a plant-made oral vaccine?

How are agencies likely to classify an edible vaccine — biologic, food, or a new category? Any precedent from trials?

Prof. L. MondalProf. L. MondalPolicyEthics
9 replies1.1k views1d ago
12votes

Quantifying antigen dose per gram of fruit

Methods for reliable quantification (ELISA vs. mass spec) and normalizing dose across harvests.

N. RoyN. RoyExpressionMethods
0 replies640 views2d ago